|
|
L-3-hydroxyisobutyrate + NAD+ <=> H+ + NADH + L-2-methyl-3-oxopropionate
|
1.1.1.291
2-hydroxymethylglutarate dehydrogenase
1.1.1.31
3-hydroxyisobutyrate dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
–
|
MK
|
|
BRENDA:
BS188039
KEGG:
R05066
MetaCyc:
3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN
SABIO-RK:
4693
|
|
|
|
2-oxoglutarate + (S)-3-amino-2-methylpropanoate <=> L-glutamate + L-2-methyl-3-oxopropionate
|
2.6.1.22
(S)-3-amino-2-methylpropionate transaminase
|
–
|
MK
|
|
KEGG:
R04188
MetaCyc:
2.6.1.22-RXN
SABIO-RK:
3906
|
|
|
|
D-methylmalonate_semialdehyde <=> L-2-methyl-3-oxopropionate
|
not assigned
|
–
|
|
|
KEGG:
R11028
MetaCyc:
RXN-14056
|
|
|
|
L-2-methyl-3-oxopropionate + L-alanine <=> (S)-3-amino-2-methylpropanoate + pyruvate
|
2.6.1
2.6.1.18
beta-alanine---pyruvate transaminase
|
–
–
|
K
|
|
KEGG:
R04187
MetaCyc:
RXN-14265
|
|
|
|
L-2-methyl-3-oxopropionate + CoA + NAD+ <=> propionyl-CoA + CO2 + NADH + H+
|
1.2.1.27
methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
|
–
|
K
|
|
KEGG:
R00935
SABIO-RK:
1253
|
|
|
|
L-2-methyl-3-oxopropionate + CoA + NAD+ <=> (R)-2-methylmalonyl-CoA + NADH + H+
|
1.2.1
|
–
|
K
|
|
KEGG:
R03381
|
|
|
|
L-2-methyl-3-oxopropionate + NAD+ + H2O <=> methylmalonate + NADH + H+
|
1.2.1.3
aldehyde dehydrogenase (NAD+)
|
–
|
K
|
|
KEGG:
R03869
|
|
|
|
methylmalonate + H2O2 <=> L-2-methyl-3-oxopropionate + O2 + H2O
|
1.2.3.1
aldehyde oxidase
|
–
|
K
|
|
KEGG:
R03871
|
|
|
|
methylmalonate <=> L-2-methyl-3-oxopropionate
|
not assigned
|
–
|
K
|
|
KEGG:
R03872
|
|
|
|
cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate + H2O <=> L-2-methyl-3-oxopropionate + pyruvate
|
3.7.1
|
–
|
K
|
|
KEGG:
R09238
|
|
|
|
pyruvate + (R)-3-Amino-2-methylpropanoate <=> L-alanine + L-2-methyl-3-oxopropionate
|
2.6.1.40
(R)-3-amino-2-methylpropionate---pyruvate transaminase
|
–
|
|
|
MetaCyc:
2.6.1.40-RXN
|
|
|
|
L-2-methyl-3-oxopropionate + CoA + NAD+ + H2O <=> propionyl-CoA + HCO3- + NADH + H+
|
1.2.1.27
methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
|
–
|
M
|
|
MetaCyc:
RXN-11213
|
|
|
|
3-hydroxy-2-methylpropanoate + NAD+ <=> L-2-methyl-3-oxopropionate + NADH
|
1.1.1.31
3-hydroxyisobutyrate dehydrogenase
|
–
|
|
|
BRENDA:
BS188036
|
|